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Springer
$119.99 $114.21

The original campus of the University of Michigan was nearly a perfect square about a half-mile along a side. A street-sized walk,... appropriately called the Diag, runs diagonally across this square, connecting its southeast and northwest corners. In 1904 a new engineering building was either started or finished (I do not remember which) to house classrooms. When another engineering building was built on the expanded campus across the street from it many years later, the old building came to be known as West Engine, to distinguish it from the new East Engine. Old West Engine is (or maybe by now, was) a four-story, L-shaped structure that stood at the southeast corner of the original campus. It was built with an arch in it to straddle the Diag at the apex of the L. You walked over the Engineering Arch to get from one leg of the L to the other if you were inside the building, and you walked under it when you entered the campus from the southeast corner. Affixed to the masonry wall of the arch was a plaque I often noted in passing. It bore a quote attributed to Horace Greeley (1811-1872), who I did not know at the time was the founder, editor, and publisher of the New York Tribune. It said, simply, Young man, when theory and practice differ, use your horse sense. The suggestion seems worthy of an exclamation point instead of a period, but I do not remember if it had one. read more

Springer
$119.99 $118.47

This book addresses an important, but so far neglected, topic: the application of sensory evaluation to quality control. Although ...several articles have been pub­ lished that have discussed concepts of quality control/sensory evaluation (QC/sen­ sory) programs, Sensory Evaluation in Quality Control is the first publication that addresses this topic in a comprehensive and practical way. This book is com­ prehensive, in that it presents the sensory and statistical information that is needed to design and implement several types of QCfsensory programs at the plant level. The book is practical, in that it provides a step-by-step description of the complete process to implement such programs, and it illustrates this process through real examples encountered by various consumer products companies (e. g. , foods, personal care products, paper products). With this practical information, sensory and quality professionals can design and implement sound QC/sensory programs at the plant level. This book was developed to provide the sensory and quality professional with an overview and guide to apply, in a production facility, the unique techniques that are used to measure sensory responses. Therefore, the book is intended for QC and/or R&D personnel (e. g. , sensory managers and analysts, and quality profes­ sionals) in charge of implementing an in-plant program, as well as for the plant management and plant technical personnel (sensory coordinator and quality pro­ fessionals) who are ultimately responsible for the routine operation of the estab­ lished program. read more

Springer
$119.99 $116.19

While preparing the first edition of this textbook I attended an extension short course on writing agricultural publications. The ...message I remember was "select your audience and write to it. " There has never been any doubt about the audience for which this textbook was written, the introductory course in crop breeding. In addition, it has become a widely used reference for the graduate plant-breeding student and the practicing plant breeder. In its prepa­ ration, particular attention has been given to advances in plant-breeding theo­ ry and their utility in plant-breeding practice. The blend of the theoretical with the practical has set this book apart from other plant-breeding textbooks. The basic structure and the objectives of the earlier editions remain un­ changed. These objectives are (1) to review essential features of plant re­ production, Mendelian genetic principles, and related genetic developments applicable in plant-breeding practice; (2) to describe and evaluate established and new plant-breeding procedures and techniques, and (3) to discuss plant­ breeding objectives with emphasis on the importance of proper choice of objec­ tive for achieving success in variety development. Because plant-breeding activities are normally organized around specific crops, there are chapters describing breeding procedures and objectives for the major crop plants; the crops were chosen for their economic importance or diversity in breeding sys­ tems. These chapters provide a broad overview of the kinds of problems with which the breeder must cope. read more

Springer
$119.99 $117.35

The Second International Cryogenic Materials Conference (ICMC) was held in Boulder, Colorado, in conjunction with the 1977 Cryogen...ic Engineering Con­ ference (CEC). Special thanks must be given to the University of Colorado for their skillful hosting of these two conferences. Collaboration between the two con­ ferences has been mutually beneficial, providing the materials special ist with insight into new applications and design concepts and the cryogenic engineer with exposure to modern materials accomplishments and potentials. The Proceedings of the 1977 Cryogenic Engineering Conference are published in Volume 23 of Advances in Cryogenic Engineering. Both conferences will be held again simul­ taneously in Madison, Wisconsin, in August 1979. The success and growth of the two International Cryogenic Materials Con­ ferences have led to the formation of an ICMC Board of Directors. The board members will serve a four-year term and include: Chairman, R. P. Reed (U.S.), R. W. Boom (U.S.), A. F. Clark (U.S.), G. Hartwig (W. Germany), J. W. Morris (U.S.), M. Suenaga (U.S.), K. Tachikawa (Japan), J. Tanaka (Japan), and K. A. Yushchenko (USSR). read more

Springer
$109.00 $108.25

Pages: 115, Edition: Softcover reprint of the original 1st ed. 1971, Paperback, Springer

Springer
$109.00 $50.94

This book is an elementary and practical introduction to probability theory. It differs from other introductory texts in two impor...tant respects. First, the per­ sonal (or subjective) view of probability is adopted throughout. Second, emphasis is placed on how values are assigned to probabilities in practice, i.e. the measurement of probabilities. The personal approach to probability is in many ways more natural than other current formulations, and can also provide a broader view of the subject. It thus has a unifying effect. It has also assumed great importance recently because of the growth of Bayesian Statistics. Personal probability is essential for modern Bayesian methods, and it can be difficult for students who have learnt a different view of probability to adapt to Bayesian thinking. This book has been produced in response to that difficulty, to present a thorough introduction to probability from scratch, and entirely in the personal framework. read more

Springer
$109.00 $108.26

General Editor: Peter Calow, Department of Zoology, University of Sheffield, England The main aim of this series will be to illust...rate and to explain the way organisms 'make a living' in nature. At the heart of this - their func­ tional biology - is the way organisms acquire and then make use of resources in metabolism, movement, growth, reproduction, and so on. These processes will form the fundamental framework of all the books in the series. Each book will concentrate on a particular taxon (species, family, class or even phylum) and will bring together informa­ tion on the form, physiology, ecology and evolutionary biology of the group. The aim will be not only to describe how organisms work, but also to consider why they have come to work in that way. By con­ centrating on taxa which are well known, it is hoped that the series will not only illustrate the success of selection, but also show the constraints imposed upon it by the physiological, morphological and develop­ mental limitations of the groups. Another important feature of the series will be its organismic orien­ tation. Each book will emphasise the importance offunctional integra­ tion in the day-to-day lives and the evolution of organisms. This is crucial since, though it may be true that organisms can be considered as collections of gene-determined traits, they nevertheless interact with their environment as integrated wholes and it is in this context that individual traits have been subjected to natural selection and have evolved. read more

Springer
$109.99 $101.77

Solid state magnetism is important and attempts to understand magnetic properties have led to an increasingly deep insight into th...e fundamental make up of solids. Both experimental and theoretical research into magnetism continue to be very active, yet there is still much ground to cover before there can be a full understanding. There is a strong interplay between the developments of materials science and of magnetism. Hundreds of new materials have been dis­ covered, often with previously unobserved and puzzling magnetic prop­ erties. A large and growing technology exists that is based on the magnetic properties of materials. Very many devices used in everyday life involve magnetism and new applications are being invented all the time. Under­ standing the fundamental background to the applications is vital to using and developing them. The aim of this book is to provide a simple, up-to-date introduction to the study of solid state magnetism, both intrinsic and technical. It is designed to meet the needs and interests of advanced undergraduate students reading physics; of postgraduates in physical and materials sciences and in engineering; and also those of the practising scientist specializing in another area who requires an introduction to magnetism. read more

Springer
$109.99 $108.40

whioh the developments are appropriate in an elementary text book is open to doubt. Fortunately the proceedings of the conference ...arranged by the Society of Actuaries Research Committee in September 1974 provide an effective review of the ourrent position (Credibility, Theory and Applications, Ed. P. M. Kahn, Academic Press, 1975). It is doubtful if any practical use is now made of the Esscher approximation and the N-P method is much more convenient and of adequate accuracy in most practical work. Thus the first half of Chapter 6 is now largely of historical interest. Chapter 11 dealing with ruin probability during a finite time interval does not give an adequate view of the current importanoe of this topic but the position is fluid because of the considerable effort being expended in the search for practical methods of calcu­ lation. Formulae are, in general, complicated and involve extensive computer based quadratures or simulation techniques. The paper by Seal in the Scandinavian Actuarial Journal (The Numerical Calculation of U(w,t) the Probability of Non-ruin in an Interval (O,t) 1974) gives a recent treatment and a fairly complete list of relevant references. In many countries studies are currently in progress in the develop­ ment of models for business planning where the basic operations involve a stochastic process. Not only are insurance companies interested but in many commercial and industrial firms the needs are significant so that a very large field exists for applications. read more

Springer
$219.99 $189.32

This volume provides a comprehensive, state-of-the art review of myeloid neoplasms. The book presents updated information on epide...miology, clinical presentation, morphologic findings, molecular genomic abnormalities, pathogenesis, and target therapies. The text helps to guide accurate diagnosis, the administration of appropriate ancillary molecular tests, patient management, and investigative efforts. The book also includes over 200 illustrations, photographs, and tables. Written by experts in the field, Precision Molecular Pathology of Myeloid Neoplasms serves as a valuable resource for pathologists, hematologists/oncologists, fellows, and researchers in understanding the molecular pathology of myeloid neoplasms.   read more

Springer
$219.99 $162.55

The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology indus...tries with a broad understanding of bone and its interactions with other organ systems in safety assessments.  The book is divided into three parts.  The first part describes our current understanding of bone biology and its primary regulatory pathways.  Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to juvenile toxicology studies.  This is intended to address recent regulatory requirements to evaluate skeletal development for drugs in development for pediatric populations.  The second part of the book describes the principal techniques and methods used in bone research; understanding how these end-points are derived is fundamental to their appropriate application.  These first two parts of the book provide the background and the means to develop the concepts in part three which describes bone and its interaction with other organ systems.  The unique series of chapters in part three, contributed to by key leaders in their respective fields and in bone research, provides a comprehensive collective work.  Although constantly evolving, the crosstalk and interaction of the skeleton with several organ systems is now recognized and well documented, such as for the reproductive system, muscle and kidney, while our understanding of the interaction with other organ systems, such as the immune system and CNS, is in its infancy. Recent work highlights the key role of the skeleton in the regulation of energy metabolism and the impact this has on research in metabolic diseases such as obesity and diabetes. The hope is that this book will enlighten many and encourage more to explore the impact of new compounds on the skeleton in the development of effective and safe drugs. read more

Springer
$109.00 $108.28

The literature on queueing theory is already very large. It contains more than a dozen books and about a thousand papers devoted e...xclusively to the subject; plus many other books on probability theory or operations research in which queueing theory is discussed. Despite this tremendous activity, queueing theory, as a tool for analysis of practical problems, remains in a primitive state; perhaps mostly because the theory has been motivated only superficially by its potential applications. People have devoted great efforts to solving the 'wrong problems. ' Queueing theory originated as a very practical subject. Much ofthe early work was motivated by problems concerning telephone traffic. Erlang, in particular, made many important contributions to the subject in the early part of this century. Telephone traffic remained one of the principle applications until about 1950. After World War II, activity in the fields of operations research and probability theory grew rapidly. Queueing theory became very popular, particularly in the late 1950s, but its popularity did not center so much around its applications as around its mathematical aspects. With the refine­ ment of some clever mathematical tricks, it became clear that exact solutions could be found for a large number of mathematical problems associated with models of queueing phenomena. The literature grew from 'solutions looking for a problem' rather than from 'problems looking for a solution. read more

Springer
$109.00 $108.30

Only 14 years have passed since the first publication appeared which implicated mycoplasmas as agents of plant disease. The diseas...es them­ selves have been known for much longer; indeed clover phyllody, a typical example, was described in the seventeenth century, well before any animal mycoplasma diseases had been documented. The early history of plant mycoplasmas is described in Chapter 2 and one obvious conclusion to be drawn from the frustrating experiences of the earlier workers is that the experimental methods at their disposal were simply inadequate for the task. Progress in science depends critically upon the development of new methods. Although important advances have been made in plant and insect mycoplasmology, notably in the discovery of spiroplasmas, many intractable problems remain. Most plant myco­ plasmas cannot yet be cultured in vitro, and their natural plant habitat, the phloem, is one of the most difficult plant tissues for the experi­ menter to handle, placing severe restrictions on the type of experiments which can be performed in vivo. It is clear that radically new methods may be required to solve these problems. A survey of the progress which has been made shows that application of techniques from a wide range of disciplines has been necessary. A successful individual or group of workers must possess the skills of a plant pathologist, a plantsman, a plant physiologist, a light-and electron microscopist, a bacteriologist, a biochemist, an immunologist, an ento­ mologist, a virologist and a molecular geneticist. read more

Springer
$109.00 $108.28

MOLECULAR ENZYMOLOGY, BECAUSE OF ITS CHEMICAL AND MATHEMATICAL content, is often regarded as a formidable and forbidding topic by ...undergraduates on a biology or biochemistry course, As a result of teaching enzymology to undergraduates for a number of years, we recognize the areas which appear to cause the most common difficulties in conceptual understanding. We feel that a book treating those areas by means of a logical approach carefully developed from basic principles fills a gap in the multiplicity of enzymology texts currently available. In writing this book we h;:lVe had in mind the needs of Honours Biochemistry students, in particular those who may take a special interest in enzymology. The text covers the main bulk of the material required in the second and third years of such courses. In addition, those taking courses in Biological Chemistry may well find the book to be of central interest. The book begins with a description of the fundamentals of catalysis, illustrating these with simple chemical reactions which may be supposed to serve as models of catalytic processes. Protein structure is discussed in terms of the fundamental forces which determine the shape and dynamic behaviour of protein molecules. The approach emphasizes those features thought to be most intimately involved in the catalytic function of enzyme molecules, and is illustrated with specific examples. read more

Springer
$109.00 $102.32

Pages: 566, Edition: Softcover reprint of the original 1st ed. 1987, Paperback, Springer

Springer
$109.00 $64.25

Hardly a decade ago, membrane receptors were an attractive but largely unproven concept. Since that time enormous progress has bee...n made, and we are now able to consider receptors much more concretely. Their existence has been established, their binding properties have been determined, and in some cases, they have been highly purified and their physical-chemical properties studied. It is now even possible to visualize microscopically some receptors. This progress has resulted largely from the development of highly powerful methods. These methods are the subject of this volume. Although considerably diverse, different receptors share certain common pro­ perties, and common problems are encountered in their study. Consequently, a small number of techniques are particularly useful in studying different types of receptors. Thus, it makes sense to speak about membrane receptor methodology. A very apparent problem in the study of membrane receptors is their presence in exceedingly small quantities and in a highly impure state. Therefore, very sensitive and specific techniques are required for their detection, characterization and purification. Such sensitivity and specificity is provided by the ability of receptors to bind certain ligands with very high affmity, and it is not surprising that most of the methods described in this volume depend upon this high affinity binding. The antigen-antibody interaction is of comparable sensitivity and speci­ ficity. Recently, a number of anti-receptor antibodies have been produced or found to occur spontaneously in auto-immune diseases. Undoubtedly, more will be produced in the future. read more

Springer
$109.00 $108.50

Although as part of my general plan, this book is a continua­ tion of my earlier monograph "Protein Biosynthesis and Problems of O...ntogenesis,"* published in 1963, in all other respects it is an independent work. The earlier monograph was devoted to the analysis of many of the aspects of the problem of protein biosynthesis, and problems of inheritance and development were discussed only insofar as they are derivatives of the problems of biosynthesis. The complex act of protein biosynthesis, comprising autore­ production of the genetic material (DNA), formation of the templates of protein synthesis (messenger RNA), synthesis of amino acid carriers (transfer RNA), formation of ribosomes and polysomes, activation of amino acids, and so on, was examined in the previous monograph not merely from the standpoint of interaction between the components of this system, but also from that of their mani­ festation in actual biological systems during morphogenesis and aging of the organism. However, both morphogenesis and aging were investigated very generally, Simply as models, without any detailed analysis of their specific features and complexity. The present book is therefore a logical continuation of its prede­ cessor. It rests largely on a comprehensive analysis of the molecular-genetic and biochemical aspects of development and differentiation of living organisms, and questions of protein biosyn­ thesis are discussed briefly and generally, and only so far as is necessary for fulfillment of the primary task. • Zh. A. Medvedev. 1966. Protein Biosynthesis and Problems of Heredity. Developement. read more

Springer
$109.00

This book provides a review of methods for obtaining and analysing data from stage-structured biological populations. The topics c...overed are sam­ pling designs (Chapter 2), the estimation of parameters by maximum likelihood (Chapter 3), the analysis of sample counts of the numbers cif individuals in different stages at different times (Chapters 4 and 5), the analysis of data using Leslie matrix types of model (Chapter 6) and key factor analysis (Chapter 7). There is also some discussion of the approaches to modelling and estimation that have been used in five studies of particular populations (Chapter 8). There is a large literature on the modelling of biological populations, and a multitude of different approaches have been used in this area. The various approaches can be classified in different ways (Southwood, 1978, ch. 12), but for the purposes of this book it is convenient to think of the three categories mathematical, statistical and predictive modelling. Mathematical modelling is concerned largely with developing models that capture the most important qualitative features of population dynamics. In this case, the models that are developed do not have to be compared with data from natural populations. As representations of idealized systems, they can be quite informative in showing the effects of changing parameters, indicating what factors are most important in promoting stability, and so on. read more